Glanzmann's thrombasthenia

Glanzmann's thrombasthenia
Platelet dysfunction in which aggregation is deficient. A specific glycoprotein complex (IIb/IIIa) is absent from the plasma membrane: this seems to be the fibronectin/fibrinogen receptor and is a b3 -integrin.

Dictionary of molecular biology. 2004.

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  • Glanzmann's thrombasthenia — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 5224 ICD10 = ICD10|D|69|1|d|65 ICD9 = ICD9|287.1 ICDO = OMIM = 187800 OMIM mult = OMIM2|273800 | MedlinePlus = eMedicineSubj = med eMedicineTopic = 872 MeshID = D013915 Glanzmann s… …   Wikipedia

  • thrombasthenia — Condition in which there is defective platelet aggregation, though adherence is normal. See Glanzmann s thrombasthenia …   Dictionary of molecular biology

  • Glanzmann thrombasthenia (disease) — Glanz·mann thrombasthenia (disease) (glahntsґmən) [Eduard Glanzmann, Swiss pediatrician, 1887–1959] see thrombasthenia …   Medical dictionary

  • Glanzmann-Naegeli-Syndrom — Klassifikation nach ICD 10 D69.1 Qualitative Thrombozytendefekte Glanzmann (Naegeli )Syndrom …   Deutsch Wikipedia

  • Glanzmann-Nägeli-Syndrom — Klassifikation nach ICD 10 D69.1 Qualitative Thrombozytendefekte Glanzmann (Naegeli )Syndrom …   Deutsch Wikipedia

  • Glanzmann-Thrombasthenie — Klassifikation nach ICD 10 D69.1 Qualitative Thrombozytendefekte Glanzmann (Naegeli )Syndrom …   Deutsch Wikipedia

  • Glanzmann thrombasthenia — a hereditary platelet abnormality characterized by defective clot retraction, prolonged bleeding time, and related symptoms such as epistaxis and inappropriate bleeding. Clinically there is abnormal glass adhesion and impaired aggregation to ADP …   Medical dictionary

  • thrombasthenia — An abnormality of platelets characteristic of Glanzmann t.. SEE ALSO: Bernard Soulier syndrome. SYN: thromboasthenia. [thromb + G. astheneia, weakness] Glanzmann t. [MIM*273800] a hemorrhagic diathesis characterized by n …   Medical dictionary

  • Glanzmann — Eduard, Swiss clinician, 1887–1959. See G. disease, G. thrombasthenia …   Medical dictionary

  • Glanzmann disease — see under thrombasthenia …   Medical dictionary

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